ADNFLE (AUT. DOM. NOCTURNAL FRONTAL LOBE EPILEPSY)

Autosomal dominant nocturnal frontal lobe epilepsy (ENFL, ADNFLE, https://omim.org/entry/600513) is a partial epilepsy with frontal lobe seizure semiology. It is characterized by childhood onset of frequent violent and brief motor seizures occurring at night. The disorder may be misdiagnosed as night terrors, nightmares, hysteria, or paroxysmal nocturnal dystonia. The condition usually persists through adult life (Scheffer et al. (1994, 1995)). The disorder is clinically distinctive and relatively homogeneous, although seizure severity and specific frontal lobe seizure manifestations vary within families (Hayman et al., 1997).